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Xinyan Zhang Lab

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Xinyan Zhang
Researcher
Ph.D., Peking University, 2013
Keywords: potato, yield, transposon, functional genomics, genome ecology
Email: zhangxinyan@caas.cn
Research Interest

The primary research area of our lab involves topics within the broadly defined area of functional genomics. The initial work in the lab will use genetically homogeneous diploid potato as a model system to study yield-related traits in crops. The potato research and breeding community is taking a giant step forward by studying and improving potatoes at the diploid level. Our main research interests are in systemically dissecting the gene regulatory networks underlying plant development focusing on yield-related traits such as tuber formation, plant architecture time, flowering time. Furthermore, we work on developing cutting-edge genetic tools and platforms for the purpose of high-throughput isolation and characterization of functional genes. The second research area in our lab is investigating the organization and function of distinct niches in orderly arranged genomes, and the transposon-host interactions in eukaryotes, with a particular focus on characterizing transposon-derived genetic factors required for precision-targeting and anti-silencing mechanisms. By exploring novel modes of parasitic strategies of transposons and the dynamics of genome ecology, we aim to arrive at a more complete understanding of how eukaryotic genomes work and evolve.

Selected Publications
1. Zhang X, Zhao M, McCarty D, Lisch D. Transposable elements employ distinct integration strategies with respect to transcriptional landscapes in eukaryotic genomes. Nucleic Acids Research. 2020, 48:6685–6698.
2. Zhang X, Zhao M, Lisch D. Cost-effective profiling of Mutator transposon insertions in maize by next-generation sequencing (book chapter). Methods in Molecular Biology. 2020; (2072), 39-50.
3. Zhang X, Guo H. mRNA decay in plants: both quantity and quality matter. Current Opinion in Plant Biology. 2017 Feb;35, 138-144.
4. Zhang X, Zhu Y, Wu H, Guo H. Post-transcriptional gene silencing in plants: a double-edged sword. Science China Life Sciences. 2016 Mar;59 (3), 271-276.
5. Zhang X, Zhu Y, Liu X, Xu Y, Zhu P, Shen Y, Yusi Ji, Wen X, Hong X, Zhang C, Zhao Q, Wang Y, Lu J, Guo H. Suppression of endogenous gene silencing by bidirectional cytoplasmic RNA decay in Arabidopsis. Science. 2015 Apr;348 (6230), 120-123.
6. Zhang X, Chen Y, Lin X, Hong X, Zhu Y, Li W, He W, An F, and Guo H. Adenine phosphoribosyl transferase 1 is a key enzyme catalyzing cytokinin conversion from nucleobases to nucleotides in Arabidopsis. Molecular Plant. 2013 Sep;6(5):1661-72.


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