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Li Wang Lab

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       Introduction

  Li Wang, principle investigator. She graduated as a bachelor in biotechnology from Wuhan University in 2006 and received her Ph.D. in Plant Evolution from the Institute of Botany, Chinese Academy of Sciences in 2011. She subsequently worked as a postdoctoral researcher at Texas Tech University, Iowa State University and the University of California at Davis. As the first author or co-author, she has published a total of 8 SCI papers, including Genome Biology, New Phytologist.

  

  Working Experience

  2019.7–Present      Agricultural Genomics Institute at Shenzhen-CAAS         Principle Investigator              

  2018.7 – 2019.5     University of California, Davis, USA                                Research Scientist    

  2014.4 – 2019.6     Iowa State University                                                         Postdoctor                              

  2012.3 – 2014.3    Texas Tech University                                                         Postdoctor     

                        

  Education Experience

  2006.9–2011.7         Institute of Botany, Chinese Academy of Sciences        Ph.D        

  2009.2–2010.11       Goettingen University, Germany                                    joint PhD student     

  2002.9–2006.7         Wuhan University                                                           Bachelor     

 

  Research Interests

  Our research focuses on the genetic mechanism of plant evolution utilizing the data of multi-omics. It specifically includes: 1) to explore the origin and evolutionary mechanism of important organs in terrestrial plants with fern and lycophytes as the research subject; 2) to investigate the prevalence of deleterious mutations in the process of domestication, migration and breeding of crops employing population genetic methods.

 

  Major Achievements

  1) Through whole-genome resequencing, we unveiled the bottleneck effect of maize domestication and a series of founder effects during the process of range expansion. The population demography affected the prevalence of deleterious mutations in the maize population.

  2) We revealed the genetic mechanism of parallel highland adaptation in multiple maize populations;

  3) Using high depth whole-genome resequencing data, we explored the dynamics of deleterious mutations in 350 maize inbred lines across 60 years’ breeding history;

  4) We disclosed the genetic mechanism of sex differentiation in Populus balsamifera with employment of population transcriptomic data, and how adaptation to high latitude environments reshaped the transcriptomes of the species.

 

  Selected Publications

  1. Brian Sanderson+, Li Wang+, Peter Tiffin, Zhi-qiang Wu, Matthew S. Olson*. 2019. Sex-biased expression in flowers, but not leaves. New Phytologist doi: 10.1111/nph.15421

  2. Li Wang, Timothy Mathes Beissinger, Anne Lorant, Claudia Ross-Ibarra, Jeffrey Ross-Ibarra, Matthew Hufford. 2017. The interplay of demography and selection during maize domestication and expansion. Genome Biology 18:215.

  3. Li Wang, Peter Tiffin, Matthew Olson. 2014. Timing for success: expression phenotype and local adaptation related to latitude in the boreal forest tree, Populus balsamifera . Tree Genetics and Genomes. DOI: 10.1007/s11295-014-0731-3.

  4. Li Wang, Harald Schneider, Xianchun Zhang, Qiaoping Xiang. 2012. The rise of the Himalaya enforced the diversification of SE Asian ferns by altering the monsoon regimes. BMC Plant Biology 12:210. DOI: 10.1186/1471-2229-12-210.

  5. Li Wang, Harald Schneider, Zhiqiang Wu, Lijuan He, Xianchun Zhang, Qiaoping Xiang. 2012. Indehiscent sporangia enable the accumulation of local fern diversity at the Qinghai-Tibetan Plateau. BMC Evolutionary Biology 12:158. DOI:10.1186/1471-2148-12-158.

  6. Li Wang, Zhiqiang Wu, Nadia Bystriakova, Stephen W. Ansell, Qiaoping Xiang, Jochen Heinrichs, Harald Schneider, Xianchun Zhang. 2011. Phylogeography of the alpine fern Lepisorus clathratus on “the roof of the world”. PloS One 6: e25896. DOI: 10.1371/journal.pone.0025896.

  7. Li Wang, Xinping Qi, Qiaoping Xiang, Jochen Heinrichs, Harald Schneider, Xianchun Zhang. 2010. Phylogeny of the paleotropical fern genus Lepisorus (Polypodiaceae, Polypodiopsida) inferred from four chloroplast genome regions. Molecular Phylogenetics and Evolution 54: 211-225.

  8. Li Wang, Zhiqiang Wu, Qiaoping Xiang, Jochen Heinrichs, Harald Schneider, Xianchun Zhang. 2010. A molecular phylogeny and a revised classification of tribe Lepisoreae (Polypodiaceae) based on an analysis of four plastid DNA regions. Botanical Journal of the Linnean Society 162: 28-38.

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