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Zhonglin Tang Lab

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        Introduction

  Zhonglin Tang, Doctoral Advisor[z2] , research Professor of Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences (CAAS-AGIS), Director of the Animal Genomics Research Center. He was a visiting scholar at Harvard University in 2016. Zhonglin Tang has undertaken more than 10 projects supported by Natural Science Foundation of China (includes the National Key Project),973 Sub-topics, etc.. More than 60 papers were published on prestigious journals, such as Genome Biology. His team had won the National Technology Invention Award, Provincial Science and Technology Progress Award, China Agricultural Science and Technology Award,National Patent Silver Awardand other nationaland provincial awards. The team also obtained 16 national invention patents, 7 software copyrights and 2 international patents have been granted. Zhonglin Tang has been honored as a leader talent of National “Ten Thousand Talent Program”.

 

  Working Experience

  2017.6–Present               Agricultural Genomics Institute at Shenzhen-CAAS               research Professor,Center director                

  2015.9–2016.8               Harvard University                                                                    visiting scholar                                                 

  2014.1–2017.5               Institute of Animal Sciences -CAAS                                        research Professor

  2008.7–2013.12             Institute of Animal Sciences -CAAS                                        associate professor         

  2006.7–2008.6               Institute of Animal Sciences -CAAS                                        Postdoctoral Fellow    

 

  Education Experience

  2001.9-2006.6              Huazhong Agricultural University                          Ph.D                   

  1994.9-1998.6              Huazhong Agricultural University                          Bachelor           

 

  Research Interest

  Using high-throughput genomics, transcriptomics, metabolomics, proteomics, and gene-editing techniques to understand the molecular mechanisms underlying skeletal muscle growth and development in pigs and mice; Using biological information, molecular and cellular biology to elucidate the function and expression regulation mechanisms of skeletal muscle growth and development related genes and non-coding RNAs at the molecular, cellular and individual levels.

 

  Major Achievements

  Published the first "ultra-clear" genomic map of Chinese local pigs(Luchuan pig), and provided the reference genome sequence of Asian local breeds. Identified multiple genetic markers closely related to meat production traits by Integrated the multi-omics method and genome-wide association analysis Significant Progress. Established the world's first database of pig genome genome RNA editing site and pig skeletal muscle methylation.

 

  Selected Publication

  1. Yalan Yang, Min Zhu, Xinhao Fan, Yilong Yao, Junyu Yan, Yijie Tang, Siyuan Liu, Kui Li*,and Zhonglin Tang*. Developmental atlas of the RNA editome in Sus scrofa skeletalmuscle. 2019,DNA Research, 2019.  26(3):261-272

  2. Z Wang*, Y Yang*, S Li, K Li and Z Tang*. Analysis and comparison of long non-coding RNAs expressed in the ovaries of Meishan and Yorkshire pigs. Animal Genetics,2019,50(6):660-669.

  3. Muya Chen†, Yi Long Yao†, Yalan Yang, Min Zhu, Yijie Tang, Siyuan Liu, Kui Li and Zhonglin Tang*. Comprehensive Profiles of mRNAs and miRNAs Reveal Molecular Characteristics of Multiple Organ Physiologies and Development in Pigs. Front. Genet,2019, 10:10.3389

  4. Zishuai Wang,Xikang Feng,Zhonglin Tang* and Shuai Cheng Li*. Genome-Wide Investigation and Functional Analysis of Sus scrofa RNA Editing Sites across Eleven Tissues. 2019,Genes, 10(7):10.3390

  5. Li Zhang, Yuemeng Huang,Meng Wang, Yafen Guo, Jing Liang,* Xiurong Yang, Wenjing Qi,Yanjun Wu, Jinglei Si, Siran Zhu, Zhe Li, Ruiqiang Li, Chao Shi,* Shuo Wang, Qunjie Zhang,Zhonglin Tang, Lixian Wang, Kui Li, Ji-Feng Fei, and Ganqiu Lan*Development and Genome Sequencing of a Laboratory-Inbred Miniature Pig Facilitates Study of Human Diabetic Disease, iScience, 2019, 19:162-176

  6. Xiaofei Yu, Zishuai Wang, Hao Sun, Guanglin Niu, Kui Li and Zhonglin Tang*.Identify long non-coding MEG3 as a candidate for skeletal muscle development and meat production traits in pigs. Animal Genetics, 2018, 49(6):571-578.

  7. Guoming Liang, Yalan Yang, Hua Li, Hui Yu, Xunbi Li, Zhonglin Tang* and Kui Li*.LncRNAnet: a comprehensive sus scrofa lncRNA database. Animal Genetics, 2018, 49(6):632-635.

  8. Guoming Liang, Yalan Yang, Guanglin Niu, Zhonglin Tang*, and Kui Li*.Genome-wide profiling of Sus scrofa circular RNAs across 9 organs and 3 developmental stages, DNA Research, 2017,24(5):523-535.

  9. Jing Zhang, Zhengzhou Ying, Zhonglin Tang*, Liangqi Long, Kui Li.MicroRNA-148a promotes myogenic differentiation by targeting the ROCK1.Journal of Biological Chemistry. 2012,287 ( 25 ): 21093-101

  10. Zhonglin Tang, Yong Li, Ping Wan, Xiaoping Li, Shuhong Zhao, Bang Liu, Bin Fan, Mengjin Zhu, Mei Yu, Kui Li. LongSAGE analysis of skeletal muscle at three prenatal stages in Tongcheng and Landrace pigs. Genome Biology. 2007.8(6):R115

 

  Selected Patent

  1.唐中林,李奎,化朝举/一种基于SMAD7基因的猪活体背膘厚标记辅助选择方法/2019-02-26/中国

  2. 唐中林,李奎,赵栓平,任红艳/与猪免疫性状相关的蛋白及其编码基因及应用/2013-06-12/中国

  3. 唐中林,李奎,梁如意,周荣,杨述林,敖红,牟玉莲,崔文涛/辅助评价仔猪初生重和断奶重的方法及其专用引物/2013-11-13/中国

  4. 唐中林,孙浩,李奎,梁如意/一种鉴定或辅助鉴定猪达100kg体重日龄的方法及其专用试剂盒/2018-11-27/中国

  5. 李奎,唐中林,孙浩,梁如意/一种鉴定或辅助鉴定猪100Kg体重眼肌面积的方法及其专用试剂盒/2018-08-17/中国

  6. 李奎,鞠辉明,樊俊华,白立景,牟玉莲,杨述林,唐中林/一种制备同时表达多个基因的转基因动物的方法/2011-12-14/中国

  7.Kui Li, Huiming Ju, Junhua Fan, Lijing Bai, Yulian Mu, Shulin Yang, Zhonglin Tang, WentaoCui/Methold for preparing a transgenic animal of simultaneous multiple-gene expression/2012-09-13/国际专利

  8. 李奎,李勇,唐中林,杨述林/一种检测猪肉质性状的方法/2010-12-15/中国

  9. 李奎,刘华珍,李新云,唐中林,杨述林,崔文涛/一种猪免疫性状相关蛋白及其编码基因与应用/2010-06-02/中国

  10.敖红,张宁波,李奎,李勇,唐中林,杨述林,储明星/检测猪的抗猪瘟病性状的方法及其专用试剂盒/2013-02-06/中国

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