Agricultural Genomics Institu at Shenzhen Chinese Academy of Agricultural Sciences
Sanwen Huang

Sanwen Huang

Title: Principal Investigator

Phone: +86 (010) 82106365

E-mail: huangsanwen@caas.cn


Research Area

Dr. Sanwen Huang integrates genomics, population genetics, and molecular biology to understand the biology of plant genomes and applies genomics in crop breeding. He has contributed significantly to the foundation for genome research in the botanical families Solanaceae and Cucurbitaceae, turbocharging genome-guided breeding of crops in these families. He pioneered transforming potato from a clonally propagated tetraploid crop into a seed diploid crop through genome design.


Education

2005 Ph.D., Wageningen University, Wageningen, the Netherlands

1996 M.S., China Agricultural University, Beijing, China

1993 B.S., China Agricultural University, Beijing, China


Professional Experience

2025-            President, CAAS, Beijing, China

2022-2025  President, CATAS, Haikou, Hainan, China

2017-            Professor, AGIS, CAAS, Shenzhen, Guangdong, China

2021-2022 Vice President, CAAS, Beijing, China

2017-2022 Director General, AGIS, CAAS

2013-2017 Professor and Co-founding Director, AGIS, CAAS

2005-2017  Professor, Dean of Biotechnology Department, Institute of Vegetables and Flowers (IVF), CAAS, Beijing, China

1996-2000  Research Associate, Pepper Genetics and Breeding, IVF, CAAS


Elected Membership

2025 Foreign Member, The Royal Society

2023 Academician, Chinese Academy of Sciences


Selected Awards and Honors

2024  The World Academy of Sciences (TWAS) Award in Agriculture, Nutrition & Food Systems Sciences for 2026, The World Academy of Sciences.

2020  Shenzhen Mayor Award of Science and Technology, Shenzhen Municipal People's Government.

2020  National Award for Excellence in Innovation, Ministry of Human Resources and Social Security, China Association for Science and Technology, Ministry of Science and Technology, State-owned Assets Supervision and Administration Commission of the State Council.

2018  The State Natural Science Award (Second Prize), State Council of the People's Republic of China.

2018  Prize for Scientific and Technological Progress from the Ho Leung Ho Lee Foundation, Ho Leung Ho Lee Foundation (Hong Kong, China).

2016  Award in Basic Science from Zhou Guang Zhao Foundation, one of three awardees, China Association of Science and Technology and Zhou Guang Zhao Foundation (Hong Kong, China).


Professional Activities

2023-             Vice-president, Botanical Society of China

2023-             Executive Editor-in-Chief, Journal of Integrative Agriculture

2022-             Editor-in-Chief, aBIOTECH

2020-             Member, Academic Advisory Committee, Cell

2020-2025   Vice-president, Chinese Society of Plant Biology

2019-2023   Vice Chairman, Potato Research Committee of Chinese Crop Society

2014-             Member, Editorial Board, Molecular Plant

2013-             Member, Editorial Board, Theoretical and Applied Genetics

2012-             Member, Editorial Board, Journal of Integrative Plant Biology

2009-2014   Co-chair, International Solanaceae Genomes Consortium

2007-2012   Chair, International Cucumber Genome Initiative

2005-             Member, Chinese Society of Horticultural Sciences


Invited Plenary Talks at Selected Conferences

2025 Invited Speaker, Cell Symposia: Towards Sustainable Agriculture: Genomics, Bioengineering, and Smart Technologies, Sanya, China

2024 Invited Speaker, EMBO | EMBL Symposium: Diversity of Plants: from Genomes to Metabolism, Heidelberg, Germany

2023 Keynote Speaker, 2023 Future Science Prize Symposium: Plant Research for Future Agriculture, Hong Kong, China

2023 Plenary Speaker, SOL 2023, the XVIII Internationa Solanaceae Genome Conference, Special video plenary lecture, Montreal, Canada

2022 Invited Speaker, the 11th World Potato Congress: The Changing World of the Potato, online meeting, Dublin, Ireland

2022 Invited Speaker, 21st European Association for Potato Research (EAPR) Triennial Conference, online meeting, Krakow, Poland

2021 Invited Speaker, Gatersleben Lecture, online meeting, The Leibniz Institute of Plant Genetics and Crop Plant Research (IPK)

2019 Plenary Speaker, the 16th Solanaceae Conference: Yield and Nutrition, Jerusalem, Israel

2018 Plenary Speaker, the Agricultural Bioscience International Conference 2018 (ABIC 2018), Weifang, China, Plenary Speaker, the Potato Association of America (PAA) 102nd Annual Meeting, Boise, USA

2018 Invited Speaker, The China- UK Science Policy Dialogue on Genetic Technology, London, UK

2017 Plenary Speaker, Cold Spring Harbor Laboratory Meeting: Plant Genomes & Biotechnology, New York, USA

2017 Invited Speaker, Workshop of "Evolution of Biological Traits", Munich, Germany

2017 Plenary Speaker, the XIV Solanaceae and III Cucurbitaceae Genomics Joint Conference (SOLCUC 2017), Valencia, Spain

2016 Invited Speaker, The 13th International Symposium on Cytochrome P450 Biodiversity and Biotechnology, Vancouver, Canada


Selected Publications and Impact

Sanwen Huang has published over 180 academic papers. As the corresponding author, he has 6 papers in Nature, 2 papers in Science, 6 papers in Cell, and 9 papers in Nature Genetics. His work has received over 33,000 citations, with 18 papers recognized as ESI Highly Cited. He serves on the Cell Academic Advisory Committee and has been named a Global Highly Cited Researcher by Clarivate in 2020, 2023, and 2024.

Wang L, Li H, Ke Y, Zhu P, Li Y, Wang P, Liu H, Li Y, Chen J, Zhou S, Wan L, Dinesh-Kumar S, Dong S*, Huang S*, Plug-in strategy for resistance engineering inspired by potato NLRome, Nature, Online(2025), doi: 10.1038/s41586-025-09678-5

Xin T, Zhang Z, Zhang Y, Li X, Wang S, Wang G, Li H, Wang B, Zhang M, Li W, Tian H, Zhang Z, Xiao YL, Tang W, He C, Ding Y*, Huang S*, Yang X*, Recessive epistasis of a synonymous mutation confers cucumber domestication through epitranscriptomic regulation, Cell, 88(17)(2025), 4517-4529

Zhang Z, Zhang P, Ding Y, Wang Z, Ma Z, Gagnon E, Jia Y, Cheng L, Bao Z, Liu Z, Wu Y, Hu Y, Lian Q, Lin W, Wang N, Ye K, Wang H, Zhang J, Zhou Y, Liu L, Li S, Lucas WJ, Sarkinen T, Knapp S*, Rieseberg LH*, Liu J*, Huang S*, Ancient hybridization underlies tuberization and radiation of the potato lineage, Cell, 188(19)(2025), 5249-5265

Cheng L, Wang N, Bao Z, Zhou Q, Guarracino A, Yang Y, Wang P, Zhang Z, Tang D, Zhang P, Wu Y, Zhou Y, Zheng Y, Hu Y, Lian Q, Ma Z, Lassois L, Zhang C, Lucas WJ, Garrison E, Stein N, Stadler T, Zhou Y, Huang S*, Leveraging a phased pangenome for haplotype design of hybrid potato, Nature, 640(8058)(2025), 408-417

Zhang P*, Huang S*, Transgenerational epigenetic inheritance of cold adaptation in rice: Evidence for neo-Lamarckian concepts, Molecular Plant, 18(8)(2025), 1268-1269

Lian Q, Zhang Y, Zhang J, Peng Z, Wang W, Du M, Li H, Zhang X, Cheng L, Du R, Zhou Z, Yang Z, Xin G, Pu Y, Feng Z, Wu Q, Xuanyuan G, Bai S, Hu R, Negrao S, Bryan GJ, Bachem CWB, Zhou Y, Zhang R, Shang Y, Huang S*, Lin T*, Qi J*, A genomic variation map provides insights into potato evolution and key agronomic traits, Molecular Plant, 18(4)(2025), 570-589

Wang N*, Li H*, Huang S*, Rational Redomestication for future agriculture, Annual review of plant biology, 76(1)(2025), 637-662

Liu X, Wang S, Zeng K, Li W, Wang S, Huang S*, Wang H*, Yang X*, N-myristoyltransferase1 regulates biomass accumulation in cucumber (Cucumis sativus L.), Journal of Integrative Agriculture, 24(5)(2025), 1754-1768

Ban X, Qin L, Yan J, Wu J, Li Q, Su X, Hao Y, Hu Q, Kou L, Yan Z, Xin P, Zhang Y, Dong L, Bouwmeester H, Yu H, Yu Q, Huang S, Lin T, Xie Q, Chen Y, Chu J, Cui X*, Li J*, Wang B*, Manipulation of a strigolactone transporter in tomato confers resistance to the parasitic weed broomrape, The Innovation, 6(3)(2025), 100815

Dong Z, Liu X, Guo X, Liu X, Wang B, Shao W, Tian C, Zheng Y, Yu Q, Zhong L, Sun J, Li S, Xin T, Zhang B, Yang T, Lu H, Rose JKC, Lucas WJ, Xu X, Huang S, Liu H*, Yang X*, Developmental innovation of inferior ovaries and flower sex orchestrated by KNOX1 in cucurbits, Nature Plants, 11(4) (2025), 861-877

Xiao H, Wang Y, Liu W, Shi X, Huang S, Cao S, Long Q, Wang X, Liu Z, Xu X, Peng Y, Wang P, Jiang Z, Riaz S, Walker AM, Gaut BS, Huang S, Zhou Y*, Impacts of reproductive systems on grapevine genome and breeding, Nature Communications, 16(1)(2025), 2031

Cheng L, Bao Z, Kong Q, Lassois L, Stein N, Huang S, Zhou Q*, Genome analyses and breeding of polyploid crops, Nature Plants, (9)(2025), 1714-1728

Peng Y, Wang Y, Liu Y, Fang X, Cheng L, Long Q, Su D, Zhang T, Shi X, Xu X, Xu Q, Wang N, Zhang F, Liu Z, Xiao H, Yao J, Tian L, Hu W, Chen S, Wang H, Huang S, Gaut BS*, Zhou Y*, The genomic and epigenomic landscapes of hemizygous genes across crops with contrasting reproductive systems, Proceedings of the National Academy of Sciences of the United States of America, 122(6)(2025), e2422487122

Du M*, Sun C, Deng L, Zhou M, Li J, Du Y, Ye Z, Huang S, Li T, Yu J, Li CB*, Li C*, Molecular breeding of tomato: Advances and challenges, Journal of integrative plant biology, 67(3)(2025), 669-721

Wu Y*, Ye K, Yin J, Du R, Cao X, Lyu H, Wang Y, Lyu Y, Hu Y, Jia Y, Xu Y, Huang S, Zhang J*, Multi-omics reveals the genetic regulation and functions of long non-coding RNAs in tomato, Plant Physiology,198(4)(2025), kiaf208

Cai Y, Wang Z, Wan W, Qi J, Liu XF*, Wang Y, Lyu Y, Li T, Dong S, Huang S, Zhou S*, Time-course dual RNA-seq analyses and gene identification during early stages of plant-Phytophthora infestans interactions, Plant Physiology, 197(4)(2025), kiaf112

Wang Y, Li N, Ma C, Cai Y, Pi L, Yu S, Wang Z, Dong S, Huang S, Zhou S*, Inducible sesquiterpene synthase and a phenylpropanoid phytoalexin of eggplants (Solanum melongena) synergistically promote nonhost resistance against Phytophthora infestans, Journal of Agricultural and Food Chemistry,73(41)(2025), 26087-26100

Zhang J, Lyu H, Chen J, Cao X, Du R, Ma L, Wang N, Zhu Z, Rao J, Wang J, Zhong K, Lyu Y, Wang Y, Lin T, Zhou Y, Zhou Y, Zhu G, Fei Z, Klee H, Huang S*, Releasing a sugar brake generates sweeter tomato without yield penalty, Nature, 635(8039)(2024), 647-656

Li D, Geng Z, Xia S, Feng H, Jiang X, Du H, Wang P, Lian Q, Zhu Y, Jia Y, Zhou Y, Wu Y, Huang C, Zhu G, Shang Y, Li H, Stadler T, Yang W*, Huang S*, Zhang C*, Integrative multi-omics analysis reveals genetic and heterotic contributions to male fertility and yield in potato, Nature Communications, 15(1)(2024), 8652

Luo X, Cao L, Yu L, Gao M, Ai J, Gao D, Zhang X, John Lucas W, Huang S*, Xu J*, Shang Y*, Deep learning-based characterization and redesign of major potato tuber storage protein, Food Chemistry, 443(2024), 138556

Cao X, Du R, Xu Y, Wu Y, Ye K, Ma J, Lyu Y, Sun T, Zhu X, Liu Z, Yin J, Zhu G, Huang Z, Lyu H*, Huang S*, Zhang J*, Phytoene synthases 1 modulates tomato fruit quality through influencing the metabolic flux between carotenoid and flavonoid pathways, Horticultural Plant Journal, 10(6)(2024), 1383-1397

Zhang M, Wang B, Wang S, Xin T, Ye K*, Huang S*, Yang X*, Transcriptomic analysis on cucumber tendril reveals GLRs play important roles in thigmotropism and thigmomorphogenesis, Horticultural Plant Journal, 10(5)(2024), 1177-1186

Jiang B, Gao L, Wang H, Sun Y, Zhang X, Ke H, Liu S, Ma P, Liao Q, Wang Y, Wang H, Liu Y, Du R, Rogge T, Li W, Shang Y, Houk KN, Xiong X, Xie D, Huang S, Lei X*, Yan J*, Characterization and heterologous reconstitution of Taxus biosynthetic enzymes leading to baccatin III, Science, 383(6683)(2024), 622-629

Cheng S*, Feng C, Wingen LU, Cheng H, Riche AB, Jiang M, Leverington-Waite M, Huang Z, Collier S, Orford S, Wang X, Awal R, Barker G, O'Hara T, Lister C, Siluveru A, Quiroz-Chavez J, Ramirez-Gonzalez RH, Bryant R, Berry S, Bansal U, Bariana HS, Bennett MJ, Bicego B, Bilham L, Brown JKM, Burridge A, Burt C, Buurman M, Castle M, Chartrain L, Chen B, Denbel W, Elkot AF, Fenwick P, Feuerhelm D, Foulkes J, Gaju O, Gauley A, Gaurav K, Hafeez AN, Han R, Horler R, Hou J, Iqbal MS, Kerton M, Kondic-Spica A, Kowalski A, Lage J, Li X, Liu H, Liu S, Lovegrove A, Ma L, Mumford C, Parmar S, Philp C, Playford D, Przewieslik-Allen AM, Sarfraz Z, Schafer D, Shewry PR, Shi Y, Slafer GA, Song B, Song B, Steele D, Steuernagel B, Tailby P, Tyrrell S, Waheed A, Wamalwa MN, Wang X, Wei Y, Winfield M, Wu S, Wu Y, Wulff BBH, Xian W, Xu Y, Xu Y, Yuan Q, Zhang X, Edwards KJ, Dixon L, Nicholson P, Chayut N, Hawkesford MJ, Uauy C, Sanders D, Huang S, Griffiths S*, Harnessing landrace diversity empowers wheat breeding, Nature, 632(8026)(2024), 823-831

Garrison E*, Guarracino A, Heumos S, Villani F, Bao Z, Tattini L, Hagmann J, Vorbrugg S, Marco-Sola S, Kubica C, Ashbrook DG, Thorell K, Rusholme-Pilcher RL, Liti G, Rudbeck E, Golicz AA, Nahnsen S, Yang Z, Mwaniki MN, Nobrega FL, Wu Y, Chen H, de Ligt J, Sudmant PH, Huang S, Weigel D, Soranzo N, Colonna V, Williams RW, Prins P, Building pangenome graphs, Nature Methods, 21(11)(2024), 2008-2012

Liu Z, Wang N, Su Y, Long Q, Peng Y, Shangguan L, Zhang F, Cao S, Wang X, Ge M, Xue H, Ma Z, Liu W, Xu X, Li C, Cao X, Ahmad B, Su X, Liu Y, Huang G, Du M, Liu Z, Gan Y, Sun L, Fan X, Zhang C, Zhong H, Leng X, Ren Y, Dong T, Pei D, Wu X, Jin Z, Wang Y, Liu C, Chen J, Gaut B, Huang S, Fang J*, Xiao H*, Zhou Y*, Grapevine pangenome facilitates trait genetics and genomic breeding, Nature Genetics, 56(12)(2024), 2804-2814

Jarvis A*, Gallo-Franco J, Portilla J, German B, Debouck D, Rajasekharan M, Khoury C, Herforth A, Ahmed S, Tohme J, Arnaud E, Golden CD, Dawid C, de Haan S, DeClerck F, Feskens EJM, Fogliano V, Fritz G, Hald C, Hall R, Hart R, Henry A, Huang S, Hunter D, Imanbaeva B, Lowe A, Turner NJ, Jia G, Johnson E, Kalaiah G, Karboune S, Klade S, La Cerva GR, Lal V, Levy AA, Longvah T, Maeda-Yamamoto M, Minnis P, Nuti M, Octavio M, Osorio C, Pawera L, Peter S, Prasad R, Quave C, Shapiro HY, Sreeman S, Srichamnong W, Steiner R, Turdieva M, Ulian T, van Andel T, Wang R, Weissgold L, Yan J, de la Parra J, Periodic Table of Food Initiative for generating biomolecular knowledge of edible biodiversity, Nature Food, 5(3)(2024), 189-193

Guan J, Miao H, Zhang Z, Dong S, Zhou Q, Liu X, Beckles DM, Gu X, Huang S, Zhang S*, A near-complete cucumber reference genome assembly and Cucumber-DB, a multi-omics database, Molecular Plant, 17(8)(2024), 1178-1182

Guo M*, Lian Q, Mei Y, Yang W, Zhao S, Zhang S, Xing X, Zhang H, Gao K, He W, Wang Z, Wang H, Zhou J, Cheng L, Bao Z, Huang S, Yan J*, Zhao X*, Analyzes of pan-genome and resequencing atlas unveil the genetic basis of jujube domestication, Nature Communication, 15(1)(2024), 9320

Ye K*, Bu F, Zhong L, Dong Z, Ma Z, Tang Z, Zhang Y, Yang X, Xu X, Wang E, Lucas WJ, Huang S, Liu H*, Zheng J*, Mapping the molecular landscape of Lotus japonicus nodule organogenesis through spatiotemporal transcriptomics, Nature Communications, 15(1)(2024), 6387

Lian Q, Li S, Kan S, Liao X, Huang S, Sloan DB, Wu Z*, Association analysis provides insights into plant mitonuclear interactions, Molecular Biology and Evolution, 41(2)(2024), msae028

Sun M, Huang S, Zhou Y*, Enhancing sheepgrass through genomic exploration and targeted editing, Science China Life Science, 67(3)(2024), 629-630

Wang Y, Sun C, Ye Z, Li C, Huang S, Lin T*, The genomic route to tomato breeding: Past, present, and future, Plant Physiology, 195(4)(2024), 2500-2514

Wu Y, Li D, H Yong, Li H, Ramstein GP, Zhou S, Zhang X, Bao Z, Zhang Y, Song B, Zhou Y, Zhou Y, Gagnon E, Sarkinen T, Knapp S, Zhang C, Stadler T, Buckler ES, Huang S*, Phylogenomic discovery of deleterious mutations facilitates hybrid potato breeding, Cell, 186(11)(2023), 2313-2328

Lin X*, Jia Y, Heal R, Prokchorchik M, Sindalovskaya M, Olave-Achury A, Makechemu M, Fairhead S, Noureen A, Heo J, Witek K, Smoker M, Taylor J, Shrestha RK, Lee Y, Zhang C, Park SJ, Sohn KH*, Huang S*, Jones JDG*, Solanum americanum genome-assisted discovery of immune receptors that detect potato late blight pathogen effectors, Nature Genetics, 55(9)(2023), 1579-1588

Ma Y, Zu Y, Huang S*, Stephanopoulos G*, Engineering a universal and efficient platform for terpenoid synthesis in yeast, Proceedings of the National Academy of Sciences of the United States of America, 120(1)(2023), e2207680

Li H, Yang X, Shang Y, Zhang Z, Huang S*, Vegetable biology and breeding in the genomics era, Science China-Life Sciences, 66(2)(2023), 226-250

Wang Y, Dong Z, Ma Y, Zheng Y, Huang S*, Yang X*, Comprehensive dissection of meiotic DNA double-strand breaks and crossovers in cucumber, Plant Physiology, 193(3)(2023), 1913-1932

Wang L, Zhao F, Liu H, Chen H, Zhang F, Li S, Sun T, Nekrasov V, Huang S*, Dong S*, A modified Agrobacterium-mediated transformation for two oomycete pathogens, PLoS Pathogens, 19(4)(2023), e1011346

Li N, He Q, Wang J, Wang B, Zhao J, Huang S, Yang T, Tang Y, Yang S, Aisimutuola P, Xu R, Hu J, Jia C, Ma K, Li Z, Jiang F, Gao J, Lan H, Zhou Y, Zhang X, Huang S, Fei Z, Wang H*, Li H*, Yu Q*, Super-pangenome analyses highlight genomic diversity and structural variation across wild and cultivated tomato species, Nature Genetics, 55(5)(2023), 852-860

Han F, Yuan K, Sun W, Zhang X, Liu X, Zhao X, Yang L, Wang Y, Ji J, Liu Y, Li Z, Zhang J, Zhang C, Huang S, Zhang Y*, Fang Z*, Lv H*, A natural mutation in the promoter of Ms-cd1 causes dominant male sterility in Brassica oleracea, Nature Communications, 14(1)(2023), 6212

Yang X, Zhang L, Guo X, Xu J, Zhang K, Yang Y, Yang Y, Jian Y, Dong D, Huang S, Cheng F*, Li G*, The gap-free potato genome assembly reveals large tandem gene clusters of agronomical importance in highly repeated genomic regions, Molecular Plant, 16(2)(2023), 314-317

Zhu Y*, Zhu G, Xu R, Jiao Z, Yang J, Lin T, Wang Z, Huang S, Chong L*, Zhu J*, A natural promoter variation of SlBBX31 confers enhanced cold tolerance during tomato domestication, Plant Biotechnology Journal, (2023), 1033-1043

Chen H, Fang Y, Zwaenepoel A, Huang S, van de Peer Y*, Li Z*, Revisiting ancient polyploidy in leptosporangiate ferns, New Phytologist, 237(4)(2023), 1405-1417

Ma Y, Li D, Zhong Y, Wang X, Li L, Osbourn A, Lucas WJ, Huang S, Shang Y*, Vacuolar MATE/DTX protein-mediated cucurbitacin C transport is co-regulated with bitterness biosynthesis in cucumber, New Phytologist, 238(3)(2023), 995-1003

Hong Y, Guan X, Wang X, Kong D, Yu S, Wang Z, Yu Y, Chao Z, Liu X, Huang S, Zhu J, Zhu G*, Wang*, Natural variation in SlSOS2 promoter hinders salt resistance during tomato domestication, Horticulture Research, 10(1)(2023), uhac244

Ye Z, Lu R, Li C, Yang D, Zeng Z, Lin W, Cheng J, Yang Z, Wang L, Gao Y, Huang S, Zhang X*, Li S*, Haplotype-resolved and chromosome-level genome assembly of Colorado potato beetle, Journal of Genetics and Genomics, 50(7)(2023), 532-535

Tang D, Jia Y, Zhang J, Li H, Cheng L, Wang P, Bao Z, Liu Z, Feng S, Zhu X, Li D, Zhu G, Wang H, Zhou Y, Zhou Y, Bryan G, Buell CR, Zhang C, Huang S*, Genome evolution and diversity of wild and cultivated potatoes, Nature, 606(7914)(2022), 535-541

Zhou Y, Zhang Z, Bao Z, Li H, Lyu Y, Zan Y, Wu Y, Cheng L, Fang Y, Wu K, Zhang J, Lyu H, Lin T, Gao Q, Saha S, Mueller L, Fei Z, Stadler T, Xu S, Zhang Z, Speed D, Huang S*, Graph pangenome captures missing heritability and empowers tomato breeding, Nature, 606(7914)(2022), 527-534

Huang X*, Huang S*, Han B, Li J*, The integrated genomics of crop domestication and breeding, Cell, 185(15)(2022), 2828-2839

Ma Y, Liu N, Greisen P, Li J, Qiao K, Huang S*, Stephanopoulos G*, Removal of lycopene substrate inhibition enables high carotenoid productivity in Yarrowia lipolytica, Nature Communications, 13(1)(2022), 572

Bao Z, Li C, Li G, Wang P, Peng Z, Cheng L, Li H, Zhang Z, Li Y, Huang W, Ye M, Dong D, Cheng Z, VanderZaag P, Jacobsen E, Bachem CWB, Dong S, Zhang C, Huang S*, Zhou Q*, Genome architecture and tetrasomic inheritance of autotetraploid potato, Molecular Plant, 15(7)(2022), 1211-1226

Li D, Lu X, Zhu Y, Pan J, Zhou S, Zhang X, Zhu G, Shang Y, Huang S*, Zhang C*, The multi-omics basis of potato heterosis, Journal of Integrative Plant Biology, 64(3)(2022), 671-687

Li Z, Zheng Y, Li Y, Cheng X, Huang S*, Yang X*, Qin Y*, Genotype-specific recruitment of rhizosphere bacteria from sandy loam soil for growth promotion of Cucumis sativus var, hardwickii, Frontiers in Microbiology, 13(2022), 910644

Yu J, Wu S, Sun H, Wang X, Tang X, Guo S, Zhang Z, Huang S, Xu Y, Weng Y, Mazourek M, McGregor C, Renner SS, Branham S, Kousik C, Wechter WP, Levi A, Grumet R, Zheng Y, Fei Z*, CuGenDBv2: an updated database for cucurbit genomics, Nucleic Acids Research, 51(D1)(2022), D1457-D1464

Li H, Wang S, Chai S, Yang Z, Zhang Q, Xin H, Xu Y, Lin S, Chen X, Yao Z, Yang Q, Fei Z, Huang S, Zhang Z*, Graph-based pan-genome reveals structural and sequence variations related to agronomic traits and domestication in cucumber, Nature Communications, 13(1)(2022), 682

Wang S, Wang K, Li Z, Li Y, He J, Li H, Wang B, Xin T, Tian H, Tian J, Zhang G, Li H, Huang S, Yang X*, Architecture design of cucurbit crops for enhanced productivity by a natural allele, Nature Plants, 8(12)(2022), 1394-1407

Fang Y*, Qin X, Liao Q, Du R, Luo X, Zhou Q, Li Z, Chen H, Jin W, Yuan Y, Sun P, Zhang R, Zhang J, Wang L, Cheng S, Yang X, Yan Y, Zhang X, Zhang Z, Bai S, Van de Peer Y, Lucas WJ, Huang S, Yan J*, The genome of homosporous maidenhair fern sheds light on the euphyllophyte evolution and defences, Nature Plants, 8(9)(2022), 1024-1037

Zhong Y, Xun W, Wang X, Tian S, Zhang Y, Li D, Zhou Y, Qin Y, Zhang B, Zhao G, Cheng X, Liu Y, Chen H, Li L, Osbourn A, Lucas WJ, Huang S, Ma Y*, Shang Y*, Root-secreted bitter triterpene modulates the rhizosphere microbiota to improve plant fitness, Nature Plants, 8(8)(2022), 887-896

Zhong Y, Chen B, Wang D, Zhu X, Li M, Zhang J, Chen M, Wang M, Riksen T, Liu J, Qi X, Wang Y, Cheng D, Liu Z, Li J, Chen C, Jiao Y, Liu W, Huang S, Liu C*, Boutilier K*, Chen S*, In vivo maternal haploid induction in tomato, Plant Biotechnology Journal, 20(2)(2022), 250-252

Xin T, Tian H, Ma Y, Wang S, Yang L, Li X, Zhang M, Chen C, Wang H, Li H, Xu J, Huang S, Yang X*, Targeted creation of new mutants with compact plant architecture using CRISPR/Cas9 genome editing by an optimized genetic transformation procedure in cucurbit plants, Horticulture Research, 9(2022), uhab086

Li S, Zhang Q, Zhang H, Wang J, Sun J, Yang X, Huang S, Zhang Z*, Deletion of a cyclin-dependent protein kinase inhibitor, CsSMR1, leads to dwarf and determinate growth in cucumber (Cucumis sativus L.), Theoretical and Applied Genetics, 135(3)(2022), 915-927

Zhang C, Yang Z, Tang D, Zhu Y, Wang P, Li D, Zhu G, Xiong X, Shang Y, Li C, Huang S*, Genome design of hybrid potato, Cell, 184(15)(2021), 3873-3883

Ma L, Zhang C, Zhang B, Tang F, Li F, Liao Q, Tang D, Peng Z, Jia Y, Gao M, Guo H, Zhang J, Luo X, Yang H, Gao D, Lucas W, Li C*, Huang S*, Shang Y*, A nonS-locus F-box gene breaks self-incompatibility in diploid potatoes, Nature Communications, 12(1)(2021), 4142

Xiong X, Gou J, Liao Q, Li Y, Zhou Q, Bi G, Li C, Du R, Wang X, Sun T, Guo L, Liang H, Lu P, Wu Y, Zhang Z, Ro DK, Shang Y, Huang S*, Yan J*, The Taxus genome provides insights into paclitaxel biosynthesis, Nature Plants, 7(8)(2021), 1026-1036

Ma Y, Li J, Huang S*, Stephanopoulos G*, Targeting pathway expression to subcellular organelles improves astaxanthin synthesis in Yarrowia lipolytica, Metabolic Engineering, 68(2021), 152-161

Qin X, Zhang Z, Lou Q, Xia L, Li J, Li M, Zhou J, Zhao X, Xu Y, Li Q, Yang S, Yu X, Cheng C, Huang S*, Chen J*, Chromosome-scale genome assembly of Cucumis hystrix-a wild species interspecifically cross-compatible with cultivated cucumber, Horticulture Research, 8(1)(2021), 40

Alseekh S, Scossa F, Wen W, Luo J, Yan J, Beleggia R, Klee HJ, Huang S, Papa R*, Fernie AR*, Domestication of crop metabolomes: desired and unintended consequences, Trends in Plant Science, 26(6)(2021), 650-661

Yu X, Wang P, Li J, Zhao Q, Ji C, Zhu Z, Zhai Y, Qin X, Zhou J, Yu H, Cheng X, Isshiki S, Jahn M, Doyle JJ, Ottosen CO, Bai Y, Cai Q, Cheng C, Lou Q, Huang S, Chen J*, Whole-genome sequence of synthesized allopolyploids in Cucumis reveals insights into the genome evolution of allopolyploidization, Advanced Science, 8(9)(2021), 2004222

Wang Z, Hong Y, Li Y, Shi H, Yao J, Liu X, Wang F, Huang S, Zhu G*, Zhu J*, Natural variations in SlSOS1 contribute to the loss of salt tolerance during tomato domestication, Plant Biotechnology Journal, 19(1)(2021), 20-22

Zhang H, Li S, Yang L, Cai G, Chen H, Gao D, Lin T, Cui Q, Wang D, Li Z, Cai R, Bai S, Lucas WJ, Huang S, Zhang Z*, Sun J*, Gain-of-function of the 1-aminocyclopropane-1-carboxylate synthase gene ACS1G induces female flower development in cucumber gynoecy, Plant Cell, 33(2)(2021), 306-321

Li Y, Cao K, Li N, Zhu G, Fang W, Chen C, Wang X, Guo J, Wang Q, Ding T, Wang J, Guan L, Wang J, Liu K, Guo W, Arus P, Huang S, Fei Z*, Wang L*, Genomic analyses provide insights into peach local adaptation and responses to climate change, Genome Research, 31(4)(2021), 592-606

Zhou Q, Tang D, Huang W, Yang Z, Zhang Y, Hamilton JP, Visser RGF, Bachem CWB, Buell CR, Zhang Z, Zhang C, Huang S*, Haplotype-resolved genome analyses of a heterozygous diploid potato, Nature Genetics, 52(10)(2020), 1018-1023

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Guo S, Zheng Y, Joung JG, Liu S, Zhang Z, Crasta OR, Sobral BW, Xu Y, Huang S*, Fei Z*, Transcriptome sequencing and comparative analysis of cucumber flowers with different sex types, BMC Genomics, 11(2010), 384

Zhang S, Miao H, Gu X*, Yang Y, Xie B, Wang X, Huang S, Du Y, Sun R, Wehner TC, Genetic mapping of the scab resistance gene in cucumber, Journal of the American Society for Horticultural Science, 135(1)(2010), 53-58

Weng Y*, Johnson S, Staub JE, Huang S, An extended intervarietal microsatellite linkage map of cucumber, Cucumis sativus L., HortScience, 45(6)(2010), 882-886

Cavagnaro PF, Senalik DA, Yang L, Simon PW, Harkins TT, Kodira CD, Huang S, Weng Y*, Genome-wide characterization of simple sequence repeats in cucumber (Cucumis sativus L.), BMC Genomics, 11(2010), 569

Huang S*, Li R, Zhang Z, Li L, Gu X, Fan W, Lucas WJ, ..., Wang J*, Du Y*, Li S*, The genome of the cucumber, Cucumis sativus L., Nature Genetics, 41(12)(2009), 1275-1281

Ren Y, Zhang Z, Liu J, Staub JE, Han Y, Cheng Z, Li X, Lu J, Miao H, Kang H, Xie B, Gu X, Wang X, Du Y, Jin W*, Huang S*, Integrated genetic and cytogenetic map of the cucumber genome, PLoS One, 4(6)(2009), e5795

Han Y, Zhang Z, Liu C, Liu J, Huang S, Jiang J, Jin W*, Centromere repositioning in cucurbit species: implication of the genomic impact from centromere activation and inactivation, Proceedings of the National Academy of Sciences of the United States of America, 106(35)(2009), 14937-14941

Li Z, Huang S, Liu S, Pan J, Zhang Z, Tao Q, Shi Q, Jia Z, Zhang W, Chen H, Si L, Zhu L, Cai R*, Molecular isolation of the M gene suggests that a conserved-residue conversion induces the formation of bisexual flowers in cucumber plants, Genetics, 182(4)(2009), 1381-1385

Mueller LA*, Lankhorst RK, Tanksley SD, Giovannoni JJ, White R, Vrebalov J, Fei Z, van Eck J, Buels R, Mills AA, Menda N, Tecle IY, Bombarely A, Stack S, Royer SM, Chang S, Shearer LA, Kim BD, Jo SH, Hur CG, Choi D, Li C, Zhao J, Jiang H, Geng Y, Dai Y, Fan H, Chen J, Lu F, Shi J, Sun S, Chen J, Yang X, Lu C, Chen M, Cheng Z, Li C, Ling H, Xue Y, Wang Y, Seymour GB, Bishop G, Bryan GJ, Rogers J, Sims S, Butcher S, Buchan D, Abbott J, Beasley H, Nicholson C, Riddle C, Humphray S, McLaren K, Mathur S, Vyas S, Solanke AU, Kumar R, Gupta V, Sharma AK, Khurana P, Khurana JP, Tyagi A, Sarita, Chowdhury P, Shridhar S, Chattopadhyay D, Pandit A, Singh P, Kumar A, Dixit R, Singh A, Praveen S, Dalal V, Yadav M, Ghazi IA, Gaikwad K, Sharma TR, Mohapatra T, Singh NK, Szinay D, de Jong H, Peters S, van Staveren M, Datema E, Fiers M, van Ham RCHJ, Lindhout P, Philippot M, Frasse P, Regad F, Zouine M, Bouzayen M, Asamizu E, Sato S, Fukuoka H, Tabata S, Shibata D, Botella MA, Perez-Alonso M, Fernandez-Pedrosa V, Osorio S, Mico A, Granell A, Zhang Z, He J, Huang S, Du Y, Qu D, Liu L, Liu D, Wang J, Ye Z, Yang W, Wang G, Vezzi A, Todesco S, Valle G, Falcone G, Pietrella M, Giuliano G, Grandillo S, Traini A, D'Agostino N, Chiusano ML, Ercolano M, Barone A, Frusciante L, Schoof H, Jocker A, Bruggmann R, Spannagl M, Mayer KXF, Guigo R, Camara F, Rombauts S, Fawcett JA, Van de Peer Y, Knapp S, Zamir D, Stiekema W, A snapshot of the emerging tomato genome sequence, Plant Genome, 2(1)(2009), 78-92

Visser RGF, Bachem CWB*, de Boer JM, Bryan GJ, Chakrabati SK, Feingold S, Gromadka R, van Ham RCHJ, Huang S, Jacobs JME, Kuznetsov B, de Melo PE, Milbourne D, Orjeda G, Sagredo B, Tang X, Sequencing the potato genome: outline and first results to come from the elucidation of the sequence of the world's third most important food crop, American Journal of Potato Research, 86(6)(2009), 417-429

Liu S, Xu L, Jia Z, Xu Y, Yang Q, Fei Z, Lu X, Chen H*, Huang S*, Genetic association of ETHYLENE-INSENSITIVE3-like sequence with the sex-determining M locus in cucumber (Cucumis sativus L.), Theoretical and Applied Genetics, 117(6)(2008), 927-933

Han Y, Zhang Z, Liu J, Lu J, Huang S, Jin W*, Distribution of the tandem repeat sequences and karyotyping in cucumber (Cucumis sativus L.) by fluorescence in situ hybridization, Cytogenetic and Genome Research, 122(1)(2008), 80-88

Armstrong MR, Whisson SC, Pritchard L, Bos JI, Venter E, Avrova AO, Rehmany AP, Böhme U, Brooks K, Cherevach I, Hamlin N, White B, Fraser A, Lord A, Quail MA, Churcher C, Hall N, Berriman M, Huang S, Kamoun S, Beynon JL, Birch PR*, An ancestral oomycete locus contains late blight avirulence gene Avr3a, encoding a protein that is recognized in the host cytoplasm, Proceedings of the National Academy of Sciences of the United States of America, 102(21)(2005), 7766-7771

Huang S, van der Vossen EA, Kuang H, Vleeshouwers VG, Zhang N, Borm TJ, van Eck HJ, Baker B, Jacobsen E, Visser RGF*, Comparative genomics enabled the isolation of the R3a late blight resistance gene in potato, The Plant Journal, 42(2)(2005), 251-261

Huang S, Vleeshouwers VG*, Visser RGF, Jacobsen E, An accurate in vitro assay for high-throughput disease testing of Phytophthora infestans in potato, Plant Disease, 89(12)(2005), 1263-1267

Wang L, Zhang B*, Lefebvre V, Huang S, Daubeze AM, Palloix A*, QTL analysis of fertility restoration in cytoplasmic male sterile pepper, Theoretical and Applied Genetics, 109(5)(2004), 1058-1063

Huang S*, Vleeshouwers VG, Werij JS, Hutten RC, van Eck HJ, Visser RGF, Jacobsen E, The R3 resistance to Phytophthora infestans in potato is conferred by two closely linked R genes with distinct specificities, Molecular Plant-Microbe Interactions, 17(4)(2004), 428-435

Huang S*, Zhang B, Milbourne D, Cardle L, Yang G, Guo J, Development of pepper SSR markers from sequence databases, Euphytica, 117(2)(2001), 163-167

Zhang B, Huang S*, Yang G, Guo J, Two RAPD markers linked to a major fertility restorer gene in pepper, Euphytica, 113(2)(2000), 155-161

Wang X*, Fang Z, Huang S, Sun P, Liu Y, Yang L, Zhuang M, Qu D, An extended random primer amplified region (ERPAR) marker linked to a dominant male sterility gene in cabbage (Brassica oleracea var. capitata), Euphytica, 112(3)(2000), 267-273


Certified Varieties

2023 Shen Ai 1 (National Tomato Variety CNA20211000678), Y. Lu, S. Huang, G. Zhu, J. Zhang, H. Lu, T. Lin, Ministry of Agriculture and Rural Affairs of the People's Republic of China

2023 Shen Ai 2 (National Tomato Variety CNA20201007380), Y. Lu, S. Huang, G. Zhu, J. Zhang, H. Lu, T. Lin, Ministry of Agriculture and Rural Affairs of the People's Republic of China


Patents Granted

US 12,404,521 B2, Materials and methods for producing hybrid diploid potato. S. Huang, L. Ma, Y. Shang, C. Zhang, C. Li.

US 12,382,919 B2, Materials and methods for producing hybrid diploid potato. S. Huang, C. Zhang, P. Wang, Y. Zhu, Z. Yang, D. Tang.

EP 3719132 B1, Method for overcoming self-incompatibility of diploid potatoes. S. Huang, C. Zhang, Z. Peng, M. Ye

US 11,746,390 B2, Method for breeding self-compatible potatoes. S. Huang, C. Zhang, Z. Yang, D. Tang.

ZL202210205170.8 Application of polynucleotides, proteins, and biological materials in regulating plant tuber development, and related products and cultivation methods. S. Huang, J. Zhang, Z. Liu, Y. Jia, S. Feng.

ZL202111164336.8 A combination of SNP loci for detecting resistance to tomato leaf mold and its application. S. Huang, K. Wu, Y. Hu, Y. Lyu, E. Zhao.

ZL202111164321.1 A combination of SNP loci for detecting resistance to tomato mosaic virus and its application. S. Huang, K. Wu, Q. Lian, J. Zhang, E. Zhao.

ZL202111164297.1 A combination of SNP loci for detecting resistance to tomato verticillium wilt and its application. S. Huang, K. Wu, Y. Hu, Y. Lyu, J. Zhang.

ZL201911285375.6 Molecular markers associated with the flowering time trait in cucumber. S. Huang, S. Wang, Z. Zhang, X. Yang, H. Li, Z. Li.

ZL202111160757.3 A combination of SNP loci for detecting resistance to tomato root-knot nematode and its application. S. Huang, K. Wu, Y. Lyu, Q. Lian, Y. Hu.

ZL201910069945.1 A method for making potato self-compatible. S. Huang, C. Zhang, Z. Yang, D. Tang.

ZL202111164271.7 A combination of SNP loci for detecting resistance to tomato yellow leaf curl virus and its application. S. Huang, K. Wu, J. Zhang, Q. Lian, Y. Hu.

ZL202111164308.6 A combination of SNP loci for detecting resistance to tomato gray leaf spot and its application. S. Huang, K. Wu, Q. Lian, J. Zhang, Y. Lyu.

ZL201910108556.5 A method for overcoming self-incompatibility of diploid potatoes. S. Huang, C. Zhang, Z. Peng, M. Ye.

ZL201811572281.2 A method for selecting parents for hybrid potato breeding. S. Huang, C. Zhang, D. Tang.

ZL202110631788.6 A method for improving enzyme. S. Huang, Y. Shang, X. Zhang, Y. Yao, W. Luo.

ZL201911230001.4 StSCI protein for changing self-incompatibility of diploid potato materials. S. Huang, L. Ma, Y. Shang, C. Zhang, C. Li.

ZL201910721010.7 A transcription factor involved in regulating cucurbitacin synthesis in melon and its application. S. Huang, Y. Ma, Y. Shang, Z. Zhang.

ZL201611124605.7 A transcription factor involved in regulating cucurbitacin synthesis in melon and its application. S. Huang, Y. Ma, Y. Shang, Z. Zhang.

ZL201611124606.1 A transcription factor involved in regulating cucurbitacin synthesis in watermelon and its application. S. Huang, Y. Ma, Y. Shang, Z. Zhang.

ZL201410642693.4 Gene controlling the tendrilless trait in cucumber and SNP markers associated with the cucumber tendril trait. S. Huang, S. Wang, Z. Zhang, X. Yang, G. Shao, J. Qi.

ZL201410529172.8 SNP markers associated with the fruit bitterness trait in cucumber and their application. S. Huang, Y. Shang, H. Chen, Y. Ma, Q. Zhou, Z. Zhang.

ZL201410273647.1 Molecular markers associated with fruit color traits in tomato and their application. S. Huang, G. Zhu, T. Lin, J. Zhang, Y. Lun, Y. Du, X. Wang.

ZL201310376574.4 Gene cluster involved in cucurbitacin C synthesis in cucumber and its application. S. Huang, Y. Shang, Z. Zhang, Y. Ma, H. Zhang, Y. Li.