Objectives
We focus on synthetic breeding, plant secondary metabolite research and artificial chromosomes development. We are performing gene network data mining and metabolic pathways analysis. We are promoting genome-wide design breeding and omics-driven plant artificial design to build a modern agricultural breeding research platform.
Introduction
Supported by big biology data and integrated large research teams, the Synthetic Biology Center aims to develop a world leading R&D center on plaAgricultural Synthetic Biology Centernt breeding and natural products while strive to decipher cutting-edge problems in agricultural synthetic biology. We focus on synthetic and genome designed breeding, plant secondary metabolite research and artificial chromosomes development. We are performing gene network data mining and metabolic pathways analysis.The Center is certified as "Key Laboratory of Synthetic Biology of the Ministry of Agriculture and Rural Development", "Shenzhen Key Laboratory of Agricultural Synthetic Biology", and "Shenzhen Hybrid Potato Engineering Research Center".
Research Areas
Research Areas 1
Establishment of a genome design and directional breeding platform to accelerate the development of new crop varieties with high yield and high quality. Based on omics data, through research on the pathways and regulatory networks of genes controlling crop agronomic traits, combined with optimal design of molecular interaction network modules.
Research Areas 2
Establishment of a plant chassis biology-based anabolic construction system for the development and industrialization of plant resources of special, social and economic importance. By establishing a functional multi-omics plant secondary metabolite analysis and design system, the Center conducts mining of important agronomic traits, functional small molecule related pathways and regulatory networks, combined with whole genome editing and artificial chromosome synthesis technology.
Research Areas 3
Establishment of a technological platform for the design and modification, chromosome editing, synthesis and assembly of ultra-long eukaryotic chromosomes, and synthesis of artificial chromosomes that can stably exist in model plants or crop species, such as small standing bowl moss or potatoes. Through the development of artificial chromosome transplantation and activation technology, construction of plants with artificial chromosomes carrying multiple resistance genes and different natural product, metabolic pathways will be analyzed to provide a basis for the realization of relevant industrial applications based on plant artificial chromosomes.
PI
Research Team
Economic Crop Genome Design Breading Innovation Team:
Agricultural Transcriptomics and Metabolomics Innovation Team:
Agricultural Biosynthesis Technology Innovation Team:
