崔鹏

崔鹏

研究员、博士生导师

动物基因组中心 科学家

cuipeng@caas.cn

 

个人简介：

崔鹏于中国科学院北京基因组研究所博士毕业，主要从事基因组学、转录组学、生物信息学和植物抗逆方向的研究工作，在领域内已发表SCI论文37篇，累计引用次数约700次；其中第一和并列第一作者论文20篇。近五年，申请人主要通过比较转录组学和蛋白功能实验相结合的方式，研究植物基因转录后调控（包括RNA剪接准确性，可变剪接和mRNA的降解）的分子机制，以及基因转录后调控在植物抗逆（主要涉及抗盐）中的作用。其主要的研究成果以第一作者身份发表在the Plant Cell（第一作者）, Genome Biology（第一作者），Molecular Plant(第一作者)，PLOS Genetics（并列第一作者）等国际著名期刊。

 

工作经历：

2009年7月-2010年1月，助理研究员，中国科学院北京基因组研究所

2010年2月-2011年3月，研究科学家，沙特阿卜杜拉国王科技大学

2011年4月-2012年3月，博士后，美国威斯康星医学院癌症中心

2012年5月-2016年4月，研究科学家，沙特阿卜杜拉国王科技大学

2016年5月-至今，青年英才，中国农业科学院农业基因组研究所

 

学习经历：

2000年9月-2004年7月，理学学士，沈阳化工大学生物工程系

2004年9月-2009年7月，理学博士，中国科学院北京基因组研究所

 

学术论文：

第一作者论文

1.Cui, P., Lin, Q., Fang, D., Zhang, L., Li, R., Cheng, J., Gao, F., Shockey, J., Hu, S., & Lu, S. 2018. Tung Tree (Vernicia fordii, Hemsl.) Genome and Transcriptome Sequencing Reveals Co-Ordinate Up-Regulation of Fatty Acid beta-Oxidation and Triacylglycerol Biosynthesis Pathways During Eleostearic Acid Accumulation in Seeds. Plant Cell Physiol, 59(10): 1990-2003.

2.Wu Z#, Fang D#, Yang R#, Gao F, An X, Zhuo X, Li Y, Yi C, Zhang T, Liang C, Cui P*, Cheng Z*, et al. De novo genome assembly of Oryza granulata reveals rapid genome expansion and adaptive evolution. Communications Biology 2018;1.

3.Cui P#, Chen T#, Ding F, Ali S, Xiong L*. The protein phosphatase FRY2 interacts with eIF4AIII and UPF3 and is essential for nonsense-mediated mRNA decay in Arabidopsis, The Plant Cell 2016, 28(3):770-85. 

4.Cui P, Xiong L*. Environmental Stress and Pre-mRNA Splicing. Molecular Plant 2015, p1302–1303.

5.Cui P#, Zhang S#, Ding F, Ali S, Xiong L*: Dynamic regulation of genome-wide pre-mRNA splicing and stress tolerance by the Sm-like protein LSm5 in Arabidopsis. Genome Biology 2014, 15:R1.

6.Ding F#, Cui P#, Wang Z, Zhang S, Ali S, Xiong L*: Genome-wide analysis of alternative splicing of pre-mRNA under salt stress in Arabidopsis. BMC genomics 2014, 15:431.

7.Chen T#, Cui P#, Chen H, Ali S, Zhang S, Xiong L*: A KH-domain RNA-binding protein interacts with FIERY2/CTD phosphatase-like 1 and splicing factors and is important for pre-mRNA splicing in Arabidopsis. PLoS Genetics 2013, 9:e1003875.

8.Liu P#, Morrison C#, Wang L, Xiong D, Vedell P, Cui P*, et al: Identification of somatic mutations in non-small cell lung carcinomas using whole-exome sequencing. Carcinogenesis 2012, 33:1270-1276.

9.Cui P, Liu W, Zhao Y, Lin Q, Zhang D, Ding F, et al: Comparative analyses of H3K4 and H3K27 trimethylations between the mouse cerebrum and testis. Genomics Proteomics Bioinformatics 2012, 10:82-93.

10.Cui P, Liu W, Zhao Y, Lin Q, Ding F, Xin C, et al: The association between H3K4me3 and antisense transcription. Genomics Proteomics Bioinformatics 2012, 10:74-81.

11.Cui P, Lin Q, Ding F, Hu S, Yu J: The transcript-centric mutations in human genomes. Genomics Proteomics Bioinformatics 2012, 10:11-22.

12.Cui P, Ding F, Lin Q, Zhang L, Li A, Zhang Z, et al: Distinct contributions of replication and transcription to mutation rate variation of human genomes. Genomics Proteomics Bioinformatics 2012, 10:4-10.

13.Cui P, Lin Q, Zhang L, Ding F, Xin C, Zhang D, et al: The Disequilibrium of Nucleosomes Distribution along Chromosomes Plays a Functional and Evolutionarily Role in Regulating Gene Expression. PLoS ONE 2011, 6.

既非第一作者又非通讯作者论文

1.Zhang S, Zhan X, Xu X, Cui P, Zhu J, Xia Y, and Xiong L*. Two domain-disrupted hda6 alleles have opposite epigenetic effects on transgenes and some endogenous targets. Scientific Reports 2015, 5:17832.

2. Chen T, Cui P, Xiong L*. The RNA-Binding protein HOS5 and Serine/Arginine-Rich Proteins RS40 and RS41 participate in miRNA biogenesis in Arabidopsis. Nucleic Acids Research 2015, gkv751.

3. Zhao H#, Lu S#, Li R, Chen T, Zhang H, Cui P, Ding F, et al: The Arabidopsis DIG6 gene encodes a large 60S subunit nuclear export GTPase 1 that is involved in ribosome biogenesis and affects multiple auxin-regulated development processes. Journal of Experimental Botany 2015, 66(21): 6863-75.

4.Xin C#, Liu W#, Lin Q, Zhang X, Cui P, Li F, et al: Profiling MicroRNA Expression during Multi-staged Date Palm (Phoenix dactylifera L.) Fruit Development. Genomics 2015, 105(4):242-51.

5. Ma L, Cui P, Zhu J, Zhang Z, Zhang Z: Translational selection in human: more pronounced in housekeeping genes. Biology Direct 2014, 9:17.